Search Tag: Sepsis

Pancreatic Stone Protein Testing Reduces Expenditure in Sepsis

2022 02 Aug

Sepsis is a life-threatening organ dysfunction and a cause of significant morbidity and mortality. In addition, the high number of sepsis cases is a significant economic burden for healthcare systems. Statistics show that sepsis was the most expensive condition treated in the U.S. in 2013, costing nearly $24 billion. An analysis of Medicare claims... Read more

Venous Thromboembolism in Sepsis

2022 02 Aug

Septic patients are often affected by coagulation disorders. Hence, they are at a high risk of thrombotic complications, ranging from widespread microvascular involvement, such as disseminated intravascular coagulation, to venous thromboembolism, arising as deep vein thrombosis or pulmonary embolism. Over the years, knowledge about the interconnected... Read more

Sepsis Awareness - Patient, Public and Healthcare Professionals

2022 19 Jul

Sepsis is a preventable cause of death. Early recognition, diagnosis, and appropriate clinical management can prevent sepsis and improve outcomes. However, the condition is not widely recognised by patients and the general public. In addition, knowledge gaps also persist among healthcare professionals.  Increasing knowledge and awareness of sepsis,... Read more

Accuracy of Pancreatic Stone Protein for Diagnosis of Infection

2022 12 Jul

Severe infections cause significant morbidity and mortality among hospitalised patients. Early detection of life-threatening infections is crucial to improving outcomes. However, none of the circulating blood biomarkers that have been investigated have been found to detect life-threatening infection quickly or accurately. Despite sub-optimal results,... Read more

Trends in Antimicrobial Prescribing During Hospitalisation for Sepsis

2022 05 Jul

There have been concerns that the emphasis on rapid administration of antimicrobials for sepsis may result in an increase in the overall use of antimicrobials, even in patients without sepsis. In a study of 1,559,523 patients hospitalised at 152 hospitals in two health care delivery systems, researchers aimed to determine whether shortening the... Read more

Serial Measurement of Pancreatic Stone Protein for Detection of Sepsis

2022 27 Jun

Sepsis continues to be a challenging health problem associated with high morbidity and mortality. Approximately 48.9 million cases of sepsis were recorded worldwide in 2017, with 11 million related deaths. Sepsis guidelines emphasise the early recognition and aggressive management of this condition with early antibiotic treatment and support. If not... Read more

Intravenous Vitamin C in ICU Patients with Sepsis

2022 21 Jun

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis contributes to between a third and a half of deaths in hospitals. It is responsible for nearly 11 million deaths worldwide each year. Treatment of sepsis typically includes antimicrobial therapy, source control, and organ support. It is believed... Read more

Renal Replacement Therapy in Patients With Sepsis-Associated AKI

2022 20 Jun

Acute kidney injury (AKI) is a serious complication of sepsis. According to data from several clinical studies, AKI can occur in nearly 50% of patients with sepsis and has a mortality rate of approximately 60% at three months.  Renal replacement therapy (RRT) is used to treat AKI, but some data show that it exerts only a limited effect in patients... Read more

Therapeutic Hyperthermia and Survival in Afebrile Sepsis Patients

2022 14 Jun

Fever is an important feature of infection. However, fewer than half of patients with sepsis present with fever at the time of diagnosis. Afebrile sepsis patients have nearly twice the mortality and are at a higher risk of developing secondary infections than patients with fever.  Fever is an adaptive response to infection that may be critical... Read more