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Associate Professor of Anaesthesia and Intensive Care; Director of Anaesthesia and Intensive Care Resident Programme; Anaesthesia and Intensive Care ITD Unit Director Anaesthesia and Intensive Care ITD Unit Director
During artificial organ support, kidney injury is multifactorial and related to the high severity of patients treated with extracorporeal membrane oxygenation (ECMO). The successful delivery of continuous renal replacement therapy (CRRT) during ECMO requires a clear prescription of the target solute clearance and fluid removal rate based on the cumulative fluid balance and physiological variables....
READ MORECritical care ultrasound examination should be considered in specific situations in the intensive care unit. It has become increasingly important to understand and master all the possible applications and future innovations of ultrasonography in the critical care setting. Point of care application of ultrasound has been widely validated as an essential imaging technique in the...
READ MOREThe importance of clearly defining sepsis, improving early recognition strategy, and increasing the understanding of innate and adaptive immune system derangements that facilitate the development of sepsis. The improvement in mortality outcomes of patients with sepsis is attributable to the early recognition of sepsis, better adherence to guidelines, and a prompt organisation's responsiveness....
READ MOREBacteria play a fundamental role in human life. Given the many roles of gut microbiota in critical illness and other pathological conditions, it is important to target therapeutical interventions to restore, preserve and enrich its composition. Introduction Bacteria play, for better or worse, a fundamental role in human life. As multidrug resistant bacterial infections are increasing...
READ MOREJoin our panellists on October 12 at 16:00 CET as they discuss the role of microbiome in critical illness, possible complications and potential microbiome treatment strategies and approaches. Register here ! Moderator JEAN-LOUIS VINCENT Editor-in-Chief ICU Management & Practice Professor Department of Intensive Care Erasme Hospital Université libre de Bruxelles Brussels, B
READ MOREOxygen therapy and mechanical ventilation in patients with COVID-19 and steps to choose the right therapeutic strategy for each patient. Introduction Severe acute respiratory syndrome coronavirus CoV-2 is the highly contagious viral agent responsible for the ongoing COVID-19 pandemic. COVID-19 is the name of the syndrome caused by SARS-CoV-2 infection. Common signs of infection include...
READ MORE“The success of intensive care has not to be measured only by survival statistics, as though each death is a medical failure. It has to be measured by the quality of lives preserved or restored and by the quality of dying of those in whose interest is to die.” This statement of G. R. Dunstan, Prof. of Morals and Social Theology, dating back to 1995, represents a warning to all intensivists. Since...
READ MOREMechanisms of endotoxin-induced multi-organ damage. Endotoxin-induced sepsis remains a leading cause of mortality in intensive care units (ICUs) worldwide. Lipopolysaccharide (LPS) identification by the immune system triggers a cascade of signalling pathways, leading to the release of several cytokines and chemokines, which orchestrate the antimicrobial and inflammatory response, though...
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