Search Tag: vascular events

Cardiology Management

2019 01 Dec

Aspirin (acetylsalicylic acid) has the unique ability to to irreversibly acetylate serine in the active site of cyclo-oxygenase (COX), permanently blocking its action in prostaglandin synthesis. This results in analgesic, antipyretic, and anti-inflammatory effects. In the platelet, it has a more durable and sustained effect. However, while aspirin...Read more

Cardiology Management

2019 07 Feb

According to data from 27 randomised trials in the Cholesterol Treatment Trialists' (CTT) Collaboration database, each 1.0 mmol/L reduction in LDL cholesterol with statin therapy reduces the risk of major vascular events by about a fifth. This risk reduction was observed with similar proportions in men and women.  However, rates of use of...Read more