Search Tag: proton pump inhibitors

ICU Management

PEPTIC Trial: Preventing Stress Ulcers in ICU Patients

2020 26 Jan

Approximately 2.5% of adults acutely admitted to an ICU develop upper gastrointestinal bleeding. 70% of these patients are prescribed stress ulcer prophylaxis. Proton pump inhibitors are the most commonly prescribed drugs as they reduce bleeding risk. However, there are some clinicians who prescribe histamine-2 receptor blockers. But this practice... Read more

ICU Management

Receptor blockers superior to proton pump inhibitors in preventing GI bleeding

2018 20 Jun

Proton pump inhibitors (PPIs) and histamine type-2 receptor blockers (H2Bs) are the main stress ulcer prophylactic agents prescribed by critical care providers. According to results of a new study, H2Bs were robustly and consistently associated with significantly lower risk of clinically important gastrointestinal bleeding (CIGIB) compared to PPIs... Read more