Search Tag: bleeding

Treatment Options for Factor-Xa Inhibitor-Related Bleeding

2019 26 Sep

Specific treatment options for factor Xa inhibitor-related bleeding, focusing on drugs like rivaroxaban, apixaban, and edoxaban.   Non-vitamin K oral anticoagulants (NOACs/DOACs) are direct reversible inhibitors of factor Xa. These drugs are also reversible inhibitors versus warfarin or other vitamin K antagonist that are used in Europe. Anticoagulants... Read more

European guideline on managing post-traumatic bleeding: 5th edition

2019 02 Apr

An updated guideline on the management of significant bleeding and coagulopathy following major trauma has been released by the pan-European, multidisciplinary Task Force for Advanced Bleeding Care in Trauma. The document, published in the journal Critical Care, includes recommendations intended to guide the management of patients during the early... Read more

Is pre-hospital coagulation management in trauma feasible?

2018 01 Jun

Coagulation management remains a formidable challenge in severely bleeding trauma patients. A strong rationale suggests starting treatment of trauma-induced coagulopathy in the pre-hospital phase. The burden of trauma is increasing worldwide, particularly in less well-resourced nations. There are an estimated 5 million deaths per year, more... Read more

Are newer anticoagulants safer than warfarin?

2018 03 Apr

A new study compared outcomes among patients with atrial fibrillation hospitalised for bleeding after starting anticoagulation (warfarin, dabigatran, or rivaroxaban). Results show rivaroxaban and dabigatran were associated with shorter hospitalisations; however, there were no differences in 30- and 90-day mortality. These findings suggest bleeding... Read more

AABB Guideline for Platelet Transfusions

2014 20 Nov

The AABB, formerly the American Association of Blood Banks, has developed a guideline on appropriate use of platelet transfusion in adult patients. The new guideline published in the Annals of Internal Medicine emphasises judicious use of the procedure to reduce patient risk and conserve resources. The guideline was developed following a systematic... Read more

ICU Volume 14 - Issue 3 - Autumn 2014

2014 24 Sep

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