Search Tag: Sepsis

ICU Management

Trends-in-sepsis-related-mortality-in-the-u-s

2021 27 Jul

Sepsis is a life-threatening organ dysfunction. It is the leading cause of death in the U.S. It is also one of the most expensive conditions to treat. However, the burden of sepsis-related mortality in the U.S. in recent years is not well-characterised. Previous studies utilise hospital databases and electronic health records to determine trends, but...Read more

ICU Management

Association-of-volume-of-sepsis-cases-and-mortality

2021 06 Jul

Sepsis is a leading cause of death worldwide and is also associated with a high burden of patient mortality.  This burden is expected to increase as populations age. Patients with sepsis typically require high-cost interventions in ICUs. Even with urgent treatment, the probability of death still remains high. However, ICUs that have more experience...Read more

Executive Health Management

Algorithm-that-predicts-deadly-hospital-infection-misses-67-of-cases

2021 28 Jun

A study published in JAMA Internal Medicine found that a system used to identify cases of sepsis missed most instances and frequently issued false alarms. Sepsis accounts for nearly 1 million hospitalisations in the US annually and is a major contributor to hospital length of stay, healthcare costs, and in-hospital mortality (up to 15%)....Read more

Sepsis

New-data-confirms-the-clinical-benefit-of-psp-for-the-diagnosis-of-severe-infections

2021 28 May

Critical Care, the top-ranked open access journal in the field of critical care medicine, published the results of a study led by Lausanne University Hospital’s Dr Philippe Eggimann and Bern University Hospital’s Dr Yok-Ai Que this month [1]. The authors analyzed pooled data from five cohorts showing that the Pancreatic stone protein (PSP) biomarker...Read more

ICU Management

Culture-negative-and-culture-positive-sepsis-or-septic-shock

2021 19 May

Incidence of sepsis and septic shock has been increasing consistently, and the morbidity and mortality associated with this is an area of concern. Mortality from sepsis and septic shock is quite high, ranging between 20 to 40%. Guidelines for sepsis and septic shock recommend the application of broad-spectrum antibiotics. There is clinical evidence...Read more

ICU Management

Antibiotic-delay-intervals-mortality-among-patients-with-suspected-sepsis

2021 27 Apr

Timely delivery of antibiotics is a major cornerstone of sepsis therapy. Clinical evidence suggests that every one-hour delay in antibiotics after emergency department (ED) triage or the onset of organ dysfunction or shock could result in a 3-7% increase in the odds of a poor outcome. The Surviving Sepsis Campaign (SSC) guidelines recommend antibiotic...Read more

Sepsis

The-psp-biomarker-rises-earlier-than-crp-and-pct-in-sepsis-a-new-study-shows

2021 20 Apr

Sepsis is a global healthcare problem, with 50 million cases each year and 11 million related deaths  1 . It’s the life-threatening complication of an infection, in which the host’s immune response to a pathogen damages its own organs. The clinical diagnosis of sepsis relies mostly on signs and symptoms that are neither sensitive nor specific enough...Read more

ICU Management

The-challenge-of-admitting-a-very-old-patient-with-sepsis-to-an-intensive-care-unit

2021 19 Apr

Sepsis incidence in very old patients is high and related mortality and morbidity are a major health concern. Frailty and severity of illness, not just age or sepsis diagnosis, are the determinant factors in outcome. Early identification and treatment are decisive in their survival. N owadays, we are facing some important facts: there has...Read more

ICU Management

Great-symposium-on-the-psp-sepsis-biomarker-hosted-by-abionic-and-palex-at-the-galisepsis-2021

2021 08 Apr

On April 6th, Abionic and Palex joined forces to participate in the first day of GaliSepsis, the National Sepsis Course hosted and organized virtually by the Ourense University Hospital Complex (CHUO) in Spain. With the aim of updating the most important concepts and reviewing the latest developments in the management of patients with sepsis, three...Read more

ICU Management

Biomarkers-to-identify-acute-kidney-injury-for-early-sepsis-detection

2021 23 Mar

Early recognition of sepsis is vital for improving patient outcomes. If detected on time, sepsis can be treated with antibiotics and source control, recognition and reversal of shock and organ support. The three most common organ dysfunctions in sepsis are cardiovascular, renal and respiratory. Cardiovascular and respiratory organ dysfunctions are...Read more

ICU Management

Resurgence-of-the-bun-creatinine-ratio-in-severe-illness-covid-19-sepsis-and-trauma-1

2021 31 Mar

Speakers John Toffaletti, Ph.D. Professor of Pathology, Director of ABG and CPED Labs Duke University Medical Center Dennis Begos, MD, FACS, FACRS Associate Medical Director, Medical and Scientific Affair Nova Biomedica l Find Nova Medical On Social Media Read more

ICU Management

Twenty-lessons-from-2020-with-a-focus-on-the-icu-perspective

2021 22 Feb

2020 has been an unusual year. As we begin 2021, it is important for intensivists to look back over what has happened and see whether lessons can be learned from our combined experiences . T he year 2020 has been unusual in so many ways and as we start a new year, it is interesting and important as intensivists to look back and reflect on what...Read more

ICU Management

44th-annual-conference-on-shock

2021 12 Oct

Find Shock Society On Social Media Read more

ICU Management

Orthos-vitros-r-b-r-a-h-m-s-pct-assay-for-sepsis-now-available

2020 06 Dec

Ortho Clinical Diagnostics , a global leader of in vitro diagnostics dedicated to improving and saving lives through innovative laboratory solutions, received CE Mark for its VITROS ®  B•R•A•H•M•S PCT (Procalcitonin) assay, now commercially available to help clinicians identify sepsis and other severe bacterial infections. Ortho’s newest assay is available...Read more

ICU Management

Atrial-fibrillation-and-sepsis-a-life-threatening-combination

2020 08 Oct

  Almost half of the patients with sepsis suffer from myocardial depression and a reduced ejection fraction. Sepsis can also cause changes in circulating volume, vascular tone, and coronary blood flow, all of which affect heart function and heart rate. Serum catecholamine levels and direct measurements of renal sympathetic nerve activity have shown...Read more

ICU Management

Early-identification-of-sepsis-web-symposium

2020 17 Nov

Speakers Prof. Dr Steven Opal Alpert Medical School of Brown University, USA Dr Bruno Francois Centre Hospitalier Universitaire de Limoges, France Dr Angelo Giacomucci Unita di Terapia Intensiva, Azienda Ospedaliera di Perugia, Italy Dr Phillipe Eggimann Centre Hopsitalier Universitaire Vaudois, Switzerland   Find Abionic on Social...Read more

ICU Management

Covid-19-still-poorly-understood

2020 02 Oct

During the first few months of the coronavirus disease, it was being suggested that severe COVID-19 may represent a hyperimmune disorder, similar to secondary haemophagocytic lymphohistiocytosis (sHLH) and macrophage activation syndrome (MAS). Cytokine storm, elevated plasma levels, ferritin and inflammatory biomarkers are all typical signs of sHLH/MAS....Read more

ICU Management

Promising-techniques-in-sepsis-after-cardiac-surgery

2020 14 Sep

The purpose of this article is to give an up-to-date, comprehensive review on the utilisation of extracorporeal blood purification techniques and immunostimulation in septic patients after cardiac surgery. Introduction Sepsis is a potentially life-threatening state caused by an infection and an inadequate, dysregulated host immune...Read more

ICU Management

Advances-in-sepsis-research-new-tools-against-one-of-the-oldest-diseases

2020 14 Sep

Sepsis and septic shock are the leading causes of death in the ICU. With an estimated mortality rate of 40-60%, septic shock is in the focus of adult critical care medicine. It is broadly accepted that intervention in the very early phase of sepsis before the complex inflammatory host response is initiated should be one major area that clinical research...Read more

Health Management

Improved-patient-assessment-with-mr-proadm

2020 29 Aug

Prof. Carlo Tascini is Head of Infectious Diseases Clinic at Udine University Hospital. Prior to that, he was the Head of First Division of Infectious Diseases Unit at Cotugno Hospital. His field of interests include endocarditis, meningitis, sepsis, MDR bacterial infection and fungal infections. HealthManagement.org spoke to Prof. Tascini about...Read more

ICU Management

Reappraisal-of-biomarkers-in-sepsis-management

2020 13 Jun

Sepsis biomarkers have an important role in the diagnosis, prognosis, and treatment of sepsis management. If timely and accurate information about biomarkers becomes available, the physician can not only make better therapeutic choices but also monitor the efficacy of the intervention in progress and adjust it accordingly.  In a previous review...Read more

ICU Management

High-risk-sepsis-survivors-and-end-of-life-care

2020 03 Mar

Sepsis is a common condition encountered in hospitals and is associated with high morbidity and mortality. However, with advances in treatment, aggressive management and early institution of antibiotics, the number of sepsis survivors has increased. Each year in the US alone, over a million patients are discharged after being treated for sepsis....Read more

ICU Management

Early-prediction-of-sepsis-from-clinical-data

2020 18 Feb

Sepsis continues to be a leading cause of death in hospitalised patients. Approximately 1.7 million individuals develop sepsis each year in the US and of these, around 270,000 die from the infection. Sepsis affects nearly 30 million patients worldwide and nearly 6 million die from sepsis each year. Billions of dollars are required to manage sepsis,...Read more

ICU Management

Vitamins-trial-no-significant-benefit-of-vitamin-c-cocktail

2020 22 Jan

Sepsis is a life-threatening condition that causes nearly one-third to half of all hospital deaths. It is also responsible for more than 5 million deaths worldwide each year. Patients with septic shock are an important subgroup of sepsis. These patients have circulatory and metabolic abnormalities that further increase their mortality risk. New treatments...Read more

ICU Management

Volume-19-issue-4-winter-2019-2020

2020 15 Jan

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ICU Management

The-future-icu

2020 15 Jan

Critical Care Medicine has existed for many years, but was only recognised as a specialty in the last 40 years or so. However, during this time, there has been a tremendous amount of change. Over the years, our understanding of different critical illnesses has improved, and our treatment strategies have become more effective. Technology has also played...Read more

ICU Management

Improving-recognition-of-neonatal-sepsis

2020 15 Jan

Improving early recognition of sepsis in the Neonatal Intensive Care Unit using machine learning models and electronic health record data. Neonatal Sepsis - Incidence and Outcomes Despite advances in knowledge and medical care, sepsis remains a major cause of morbidity and mortality in infants worldwide, claiming the lives of one...Read more

ICU Management

Diagnosis-treatment-and-management-of-the-critically-ill-patient

2020 15 Jan

Professor Rui P. Moreno works at the Intensive Care Unit of the Hospital de São José (Centro Hospitalar Universitário de Lisboa Central E.P.E) as the coordinator of the Neurocritical and Trauma ICU. Prof. Moreno has been a member of the European Society of Intensive Care Medicine (ESICM) since 1995 and became President of the Society in 2008. He...Read more