Search Tag: Sepsis
Trends-in-sepsis-related-mortality-in-the-u-s
2021 27 Jul
Sepsis is a life-threatening organ dysfunction. It is the leading cause of death in the U.S. It is also one of the most expensive conditions to treat. However, the burden of sepsis-related mortality in the U.S. in recent years is not well-characterised. Previous studies utilise hospital databases and electronic health records to determine trends, but...Read more
Association-of-volume-of-sepsis-cases-and-mortality
2021 06 Jul
Sepsis is a leading cause of death worldwide and is also associated with a high burden of patient mortality. This burden is expected to increase as populations age. Patients with sepsis typically require high-cost interventions in ICUs. Even with urgent treatment, the probability of death still remains high. However, ICUs that have more experience...Read more
Algorithm-that-predicts-deadly-hospital-infection-misses-67-of-cases
2021 28 Jun
A study published in JAMA Internal Medicine found that a system used to identify cases of sepsis missed most instances and frequently issued false alarms. Sepsis accounts for nearly 1 million hospitalisations in the US annually and is a major contributor to hospital length of stay, healthcare costs, and in-hospital mortality (up to 15%)....Read more
New-data-confirms-the-clinical-benefit-of-psp-for-the-diagnosis-of-severe-infections
2021 28 May
Critical Care, the top-ranked open access journal in the field of critical care medicine, published the results of a study led by Lausanne University Hospital’s Dr Philippe Eggimann and Bern University Hospital’s Dr Yok-Ai Que this month [1]. The authors analyzed pooled data from five cohorts showing that the Pancreatic stone protein (PSP) biomarker...Read more
Culture-negative-and-culture-positive-sepsis-or-septic-shock
2021 19 May
Incidence of sepsis and septic shock has been increasing consistently, and the morbidity and mortality associated with this is an area of concern. Mortality from sepsis and septic shock is quite high, ranging between 20 to 40%. Guidelines for sepsis and septic shock recommend the application of broad-spectrum antibiotics. There is clinical evidence...Read more
Antibiotic-delay-intervals-mortality-among-patients-with-suspected-sepsis
2021 27 Apr
Timely delivery of antibiotics is a major cornerstone of sepsis therapy. Clinical evidence suggests that every one-hour delay in antibiotics after emergency department (ED) triage or the onset of organ dysfunction or shock could result in a 3-7% increase in the odds of a poor outcome. The Surviving Sepsis Campaign (SSC) guidelines recommend antibiotic...Read more
The-psp-biomarker-rises-earlier-than-crp-and-pct-in-sepsis-a-new-study-shows
2021 20 Apr
Sepsis is a global healthcare problem, with 50 million cases each year and 11 million related deaths 1 . It’s the life-threatening complication of an infection, in which the host’s immune response to a pathogen damages its own organs. The clinical diagnosis of sepsis relies mostly on signs and symptoms that are neither sensitive nor specific enough...Read more
The-challenge-of-admitting-a-very-old-patient-with-sepsis-to-an-intensive-care-unit
2021 19 Apr
Sepsis incidence in very old patients is high and related mortality and morbidity are a major health concern. Frailty and severity of illness, not just age or sepsis diagnosis, are the determinant factors in outcome. Early identification and treatment are decisive in their survival. N owadays, we are facing some important facts: there has...Read more
Great-symposium-on-the-psp-sepsis-biomarker-hosted-by-abionic-and-palex-at-the-galisepsis-2021
2021 08 Apr
On April 6th, Abionic and Palex joined forces to participate in the first day of GaliSepsis, the National Sepsis Course hosted and organized virtually by the Ourense University Hospital Complex (CHUO) in Spain. With the aim of updating the most important concepts and reviewing the latest developments in the management of patients with sepsis, three...Read more
Biomarkers-to-identify-acute-kidney-injury-for-early-sepsis-detection
2021 23 Mar
Early recognition of sepsis is vital for improving patient outcomes. If detected on time, sepsis can be treated with antibiotics and source control, recognition and reversal of shock and organ support. The three most common organ dysfunctions in sepsis are cardiovascular, renal and respiratory. Cardiovascular and respiratory organ dysfunctions are...Read more
Resurgence-of-the-bun-creatinine-ratio-in-severe-illness-covid-19-sepsis-and-trauma-1
2021 31 Mar
Speakers John Toffaletti, Ph.D. Professor of Pathology, Director of ABG and CPED Labs Duke University Medical Center Dennis Begos, MD, FACS, FACRS Associate Medical Director, Medical and Scientific Affair Nova Biomedica l Find Nova Medical On Social Media Read more
Twenty-lessons-from-2020-with-a-focus-on-the-icu-perspective
2021 22 Feb
2020 has been an unusual year. As we begin 2021, it is important for intensivists to look back over what has happened and see whether lessons can be learned from our combined experiences . T he year 2020 has been unusual in so many ways and as we start a new year, it is interesting and important as intensivists to look back and reflect on what...Read more
Orthos-vitros-r-b-r-a-h-m-s-pct-assay-for-sepsis-now-available
2020 06 Dec
Ortho Clinical Diagnostics , a global leader of in vitro diagnostics dedicated to improving and saving lives through innovative laboratory solutions, received CE Mark for its VITROS ® B•R•A•H•M•S PCT (Procalcitonin) assay, now commercially available to help clinicians identify sepsis and other severe bacterial infections. Ortho’s newest assay is available...Read more
Atrial-fibrillation-and-sepsis-a-life-threatening-combination
2020 08 Oct
Almost half of the patients with sepsis suffer from myocardial depression and a reduced ejection fraction. Sepsis can also cause changes in circulating volume, vascular tone, and coronary blood flow, all of which affect heart function and heart rate. Serum catecholamine levels and direct measurements of renal sympathetic nerve activity have shown...Read more
Esem-2020-emirates-society-of-emergency-medicine-conference
2020 10 Dec
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Early-identification-of-sepsis-web-symposium
2020 17 Nov
Speakers Prof. Dr Steven Opal Alpert Medical School of Brown University, USA Dr Bruno Francois Centre Hospitalier Universitaire de Limoges, France Dr Angelo Giacomucci Unita di Terapia Intensiva, Azienda Ospedaliera di Perugia, Italy Dr Phillipe Eggimann Centre Hopsitalier Universitaire Vaudois, Switzerland Find Abionic on Social...Read more
Covid-19-still-poorly-understood
2020 02 Oct
During the first few months of the coronavirus disease, it was being suggested that severe COVID-19 may represent a hyperimmune disorder, similar to secondary haemophagocytic lymphohistiocytosis (sHLH) and macrophage activation syndrome (MAS). Cytokine storm, elevated plasma levels, ferritin and inflammatory biomarkers are all typical signs of sHLH/MAS....Read more
Promising-techniques-in-sepsis-after-cardiac-surgery
2020 14 Sep
The purpose of this article is to give an up-to-date, comprehensive review on the utilisation of extracorporeal blood purification techniques and immunostimulation in septic patients after cardiac surgery. Introduction Sepsis is a potentially life-threatening state caused by an infection and an inadequate, dysregulated host immune...Read more
Advances-in-sepsis-research-new-tools-against-one-of-the-oldest-diseases
2020 14 Sep
Sepsis and septic shock are the leading causes of death in the ICU. With an estimated mortality rate of 40-60%, septic shock is in the focus of adult critical care medicine. It is broadly accepted that intervention in the very early phase of sepsis before the complex inflammatory host response is initiated should be one major area that clinical research...Read more
Improved-patient-assessment-with-mr-proadm
2020 29 Aug
Prof. Carlo Tascini is Head of Infectious Diseases Clinic at Udine University Hospital. Prior to that, he was the Head of First Division of Infectious Diseases Unit at Cotugno Hospital. His field of interests include endocarditis, meningitis, sepsis, MDR bacterial infection and fungal infections. HealthManagement.org spoke to Prof. Tascini about...Read more
Reappraisal-of-biomarkers-in-sepsis-management
2020 13 Jun
Sepsis biomarkers have an important role in the diagnosis, prognosis, and treatment of sepsis management. If timely and accurate information about biomarkers becomes available, the physician can not only make better therapeutic choices but also monitor the efficacy of the intervention in progress and adjust it accordingly. In a previous review...Read more
High-risk-sepsis-survivors-and-end-of-life-care
2020 03 Mar
Sepsis is a common condition encountered in hospitals and is associated with high morbidity and mortality. However, with advances in treatment, aggressive management and early institution of antibiotics, the number of sepsis survivors has increased. Each year in the US alone, over a million patients are discharged after being treated for sepsis....Read more
Early-prediction-of-sepsis-from-clinical-data
2020 18 Feb
Sepsis continues to be a leading cause of death in hospitalised patients. Approximately 1.7 million individuals develop sepsis each year in the US and of these, around 270,000 die from the infection. Sepsis affects nearly 30 million patients worldwide and nearly 6 million die from sepsis each year. Billions of dollars are required to manage sepsis,...Read more
Vitamins-trial-no-significant-benefit-of-vitamin-c-cocktail
2020 22 Jan
Sepsis is a life-threatening condition that causes nearly one-third to half of all hospital deaths. It is also responsible for more than 5 million deaths worldwide each year. Patients with septic shock are an important subgroup of sepsis. These patients have circulatory and metabolic abnormalities that further increase their mortality risk. New treatments...Read more
The-future-icu
2020 15 Jan
Critical Care Medicine has existed for many years, but was only recognised as a specialty in the last 40 years or so. However, during this time, there has been a tremendous amount of change. Over the years, our understanding of different critical illnesses has improved, and our treatment strategies have become more effective. Technology has also played...Read more
Improving-recognition-of-neonatal-sepsis
2020 15 Jan
Improving early recognition of sepsis in the Neonatal Intensive Care Unit using machine learning models and electronic health record data. Neonatal Sepsis - Incidence and Outcomes Despite advances in knowledge and medical care, sepsis remains a major cause of morbidity and mortality in infants worldwide, claiming the lives of one...Read more
Diagnosis-treatment-and-management-of-the-critically-ill-patient
2020 15 Jan
Professor Rui P. Moreno works at the Intensive Care Unit of the Hospital de São José (Centro Hospitalar Universitário de Lisboa Central E.P.E) as the coordinator of the Neurocritical and Trauma ICU. Prof. Moreno has been a member of the European Society of Intensive Care Medicine (ESICM) since 1995 and became President of the Society in 2008. He...Read more