Search Tag: Sepsis

Artificial Intelligence

The-promise-of-artificial-intelligence-in-critical-care

2023 01 Aug

Computer-based technologies, including artificial intelligence (AI) applications like ChatGPT and DALL-E, are being increasingly used and can mimic human capabilities, even passing medical board examinations. Retrospective studies have shown that machine learning (ML) applications are especially valuable in the ICU due to their diagnostic and prognostic...Read more

Sepsis

Vasopressin-loading-for-refractory-septic-shock

2023 01 Aug

Vasopressin is a potent vasopressor used to treat septic shock, acting via a different receptor than catecholamines. Previous randomised control trials have demonstrated its efficacy. However, its use can also lead to adverse effects such as ischaemia events. Therefore, it is recommended as a second-line agent after noradrenaline.   Typically,...Read more

ICU Management

Esem-2023-emirates-society-of-emergency-medicine-conference

2023 06 Dec

<marquee behavior="slide" direction="left" scrollamount="30"><h2 style="text-align: center;"><font color="#000099"><b>Find ESEM on Social Media</b> </font></h2><div style="text-align: center;"><a href=https://www.twitter.com/UAE_ESEM target="_blank"><img src="/uploads/twnew.png" style="text-align: initial;" width=85 height=85></a&Read more

Sepsis

Extracellular-vesicles-and-predicting-sepsis

2023 24 Jul

Researchers from the Medical University of South Carolina (MUSC) have identified a novel biomarker that could revolutionise sepsis treatment. Sepsis, a life-threatening condition triggered by the body's extreme response to infection, is a leading cause of death in ICUs, often resulting in organ damage and failure.   In a recent study published...Read more

Sepsis

Sepsis-associated-acute-kidney-injury-in-the-icu

2023 18 Jul

Sepsis is a frequently encountered condition that leads to severe illness and is associated with significant morbidity and mortality. It is commonly accompanied by acute kidney injury (AKI), known as sepsis-associated acute kidney injury (SA-AKI). The relationship between sepsis and AKI has been investigated in prior studies. However, the absence...Read more

Sepsis

Deaths-from-neonatal-sepsis-and-the-need-to-improve-treatment

2023 05 Jul

A global observational study jointly led by University College London (UCL) has revealed a concerning trend in the effectiveness of antibiotics to treat sepsis in newborn babies. The study, conducted across 19 hospitals in 11 countries and involving over 3,200 infants with sepsis, found a high mortality rate among infants with culture-positive sepsis...Read more

Sepsis

Using-pmx-ha-in-patients-with-sepsis

2023 28 Jun

Endotoxin can trigger immune responses and organ failure in sepsis patients. Polymyxin B hemadsorption (PMX-HA) is an extracorporeal blood purification technique to remove circulating endotoxin and prevent organ failure. While some studies have suggested that PMX-HA improves outcomes in sepsis patients, conflicting results have been observed in randomised...Read more

Sepsis

The-swiss-medtech-award-2023-goes-to-abionic

2023 13 Jun

Rapid Diagnostic Test that could save millions of lives   At Swiss Medtech Day, the most important event in the Swiss medical technology industry with around 700 attendees, Lausanne-based company Abionic, founded in 2010, was presented with the Swiss Medtech Award valued at CHF 75,000. Abionic specialises in providing rapid diagnostic tests...Read more

Sepsis

Influence-of-gender-on-age-associated-mortality-in-sepsis

2023 13 Jun

Despite advancements in medical care, sepsis remains a significant global health issue and a leading cause of hospital mortality worldwide. Numerous epidemiological studies have been conducted on sepsis, but its epidemiology remains unclear due to its heterogeneous nature.   Sepsis is characterised by an imbalanced immune response to infection....Read more

Sepsis

Early-identification-of-sepsis-dr-francois-ventura-ceem-2023

2023 16 May

The 8th Central European Emergency Medicine Congress (CEEM 2023) organized by the Polish Society for Emergency Medicine was held in Bydgoszcz, Poland. The Congress offered a diverse range of lectures, workshops, and practical sessions delivered by world-renowned experts from Poland and abroad. The event was an opportunity for medical professionals...Read more

Sepsis

Diagnostic-accuracy-of-monocyte-distribution-width-procalcitonin-and-c-reactive-protein

2023 09 May

Sepsis is characterised by a dysregulated host response to infection resulting in organ dysfunction. It poses a significant global health problem, with a high mortality risk and millions of patients affected annually. Epidemiological studies have shown that nearly 20% of septic patients require mechanical ventilation, leading to significant healthcare...Read more

Sepsis

Automated-antibiotic-dosing

2023 02 May

Sepsis is a major challenge in intensive care medicine with high morbidity and mortality. Early and proper use of antibiotics is crucial for effective treatment.   Personalising antibiotic dosing is essential. However, maintaining adequate antibiotic exposure can be challenging, particularly for critically ill patients, as changes in organ function...Read more

Sepsis

Advancements-in-sepsis-diagnosis-the-role-of-biomarkers-and-early-detection

2023 02 May

Dr François Ventura, anaesthesiologist and intensive care physician, gave a lecture on the " C urrent research on sepsis biomarkers and early diagnosis"  during the 4th World Sepsis Congress, organised by the Global Sepsis Alliance, which took place the 25 th and 26 th April 2023. He discussed the challenges of diagnosing sepsis, which requires...Read more

Sepsis

Improving-sepsis-care-insights-from-dr-philippe-eggimann-at-isicem-2023

2023 20 Apr

The International Symposium on Intensive Care and Emergency Medicine (ISICEM) is a renowned event in the medical industry, bringing together professionals from all over the world to discuss the latest developments and advancements in critical care and emergency medicine. This year's event took place from 21 to 24 April 2023 in Brussels.   One...Read more

Sepsis

Purification-therapies-from-research-to-clinical-evidence

2023 13 Apr

Aferetica held the 3 rd "Purification Therapies" Workshop in Milano from September 30 th to October 1st. The event involved more than 400 participants from all over Europe to discuss on different critical care topics and in particular on overwhelming inflammatory diseases. One of the many sessions focused on the diagnostic side of the overwhelming...Read more

Sepsis

Personalising-fluid-therapy-in-septic-shock

2023 05 Apr

Volume expansion, the initial therapeutic measure for septic shock, involves the intravenous injection of a few hundred millilitres of fluid over a few minutes. However, using fluids in septic patients is a complex strategy, with various types of fluids available. The effects of fluid boluses are inconsistent and transient, and fluids carry risks,...Read more

Sepsis

Sepsis-through-the-lens-of-complexity-theory

2023 15 Mar

Sepsis is a complex and dysregulated state involving various factors, including pathogens, host response, organ failure, and medical interventions. Despite this complexity, the necessary concepts, approaches, and methods to understand sepsis are underappreciated.   In a recent review, the authors highlight the need to understand sepsis through...Read more

ICU Management

Volume-23-issue-1-2023-1

2023 13 Mar

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ICU Management

Biomarkers-in-sepsis

2023 13 Mar

This article describes the application of existing and emerging biomarkers in the diagnosis and management of sepsis and pneumonia. Introduction: The Need for  Biomarkers  in Sepsis Sepsis is defined as a dysregulated host response to infection that results in life threatening organ dysfunction. It carries an estimated...Read more

ICU Management

Biomarkers-in-sepsis-present-and-future

2023 13 Mar

A biomarker defines a measurable indicator of a patient's medical situation that can be measured precisely and accurately. Biomarkers provide value for diagnosis, prognosis, early disease detection, risk stratification, suitable treatment (theragnostic), and trial improvement for patients with sepsis or presumed sepsis. Introduction...Read more

ICU Management

Tachycardia-in-sepsis-friend-or-foe

2023 13 Mar

An overview of tachycardia in sepsis, the importance of rate control and the beneficial effects of beta-blockers.         Sepsis and Tachycardia – Aetiologic Factors During sepsis, the sympathetic nervous system plays a key role in maintaining cardiac output and blood pressure. This is achieved through changes...Read more

Cardiology Management

Tachycardia-in-sepsis-friend-or-foe

2023 13 Mar

An overview of tachycardia in sepsis, the importance of rate control and the beneficial effects of beta-blockers.         Sepsis and Tachycardia – Aetiologic Factors During sepsis, the sympathetic nervous system plays a key role in maintaining cardiac output and blood pressure. This is achieved through changes...Read more

Sepsis

Antioxidant-anti-inflammatory-therapy-in-sepsis

2023 07 Mar

Sepsis is associated with long-term cognitive impairment and poor psychological and functional outcomes. Potential mechanisms for this include intracerebral oxidative stress and inflammation. However, there is limited knowledge about the effects of early antioxidant and anti-inflammatory therapy on cognitive, psychological, and functional outcomes...Read more

Sepsis

Sequential-extracorporeal-therapy-in-sepsis

2023 15 Feb

Sepsis and septic shock are significant causes of morbidity and mortality in critical care, with a complex and rapidly evolving clinical presentation. This involves microbial invasion, infection focus, immune response, circulating pathogen and pathogen products, immunodysregulation, organ damage, and multiple organ dysfunction. Extracorporeal therapies...Read more

Sepsis

Nanofluidic-technology-enables-rapid-quantification-of-psp-as-an-early-biomarker-of-sepsis

2023 01 Feb

In-vitro diagnostic tests allow for quick results and prompt decision-making by medical professionals in near-patient settings. The abioSCOPE® device uses nanofluidic technology to quickly measure the number of molecules in a sample using a small amount of fluid and minimal preparation, resulting in fast results. Pancreatic stone protein (PSP) is a...Read more

Sepsis

Shifting-sepsis-quality-measures-from-processes-to-outcomes

2023 31 Jan

Sepsis is a significant health issue that leads to high rates of death and disability, with over 250,000 adult deaths annually in the U.S. alone. Healthcare providers, patients, regulatory agencies, and advocates for quality improvement acknowledge the importance of preventing sepsis and improving its outcomes.  The Severe Sepsis/Septic Shock Early...Read more