Search Tag: Biomarkers

2015 11 Feb

A Massachusetts General Hospital (MGH)-led study has shown that a set of characteristics, including differences in gene expression, may indicate which patients recovering from severe burns are at greatest risk for repeat infections. The finding is published online in Annals of Surgery . "Our approach is the first to enable the prediction of repeat...Read more

2015 05 Feb

A blood profiling technique has uncovered four new biomarkers that improve the prediction of risk for heart attack or stroke within the next 15 years. The study has been published in the journal Circulation.   The blood screening technology can help doctors identify people who would benefit from early treatment. In addition, the high-throughput...Read more

2015 24 Jan

Researchers at the University of Michigan Comprehensive Care Center have conducted a new analysis that could open the door to discovery of thousands of potential new cancer biomarkers. The researchers analysed the long non-coding RNAs (lncRNAs) - a vast portion of the human genome that has not been well-explored before. It is believed that lncRNAs...Read more

2015 19 Jan

Based on results of a new study, high levels of two novel urinary biomarkers early in critical illness correlate with adverse long-term outcomes in patients with acute kidney injury (AKI). The combination of tissue inhibitor metalloproteinase-2 (TIMP-2) and IGF-binding protein-7 (IGFBP7) can identify patients with AKI who are at greater risk of death...Read more

2014 08 Nov

Note : RSNA recently announced an additional $1.27 million of funding from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) to support research by the Quantitative Imaging Biomarkers Alliance (QIBA). The funding will be used towards the development of a Quantitative Imaging Data Warehouse, research to characterise the sources...Read more

2014 07 Nov

On-the-spot tests for bacterial infections, which only take about three minutes to process, may help to reduce excessive use of antibiotics. Researchers in Denmark performed a systematic review showing that doctors who tested for the presence of bacterial infections were prescribing fewer antibiotics. Their findings are published online in The Cochrane...Read more

2014 05 Nov

More than 800 markers have been identified in the blood of cancer patients that could potentially lead to the development of a single blood test for early detection of many cancer types. In a study conducted by the UK Early Cancer Detection Consortium (ECDC), which was presented at the National Cancer Research Institute Conference in Liverpool, researchers...Read more

2014 04 Oct

A new study has identified a biomarker living beside the KLK3 gene that can predict which GS7 prostate cancer patients will have a more aggressive form of cancer, according to a Science Newsline report. The KLK3 gene is located on chromosome 19 and is responsible for encoding the prostate-specific antigen (PSA). Results of the study published in...Read more

2014 07 Sep

High-throughput biological techniques have reshaped the perspective of biomedical research allowing for fast and efficient assessment of the entire molecular topography of a cell’s physiology, providing new insights into human cancers. However, a main limitation of these techniques is the need to acquire tissue for gene expression profiling through...Read more

2014 06 Sep

Advances in science and engineering have made rapid transport from distant locations to tertiary medical centres the standard. Similarly, communication technology has changed the expectations for consultation or transmission of patient information en route. Nevertheless, a major Southeast Asia paediatric tertiary care centre, KK Women’s and Children’s...Read more

2014 10 Jun

University of Glasgow researchers have found that some microvascular complications of Type 2 diabetes can be predicted by an assessment of cardiac biomarkers. The results indicate that an underlying cardiac condition may precede peripheral microvascular disease processes. Peripheral microvascular events common to diabetic patients include nephropathy...Read more

2014 10 Apr

When someone suffers a stroke, a race against time begins, as a fast diagnosis and subsequent treatment can make the difference between life and death. According to a report published in the ACS journal Analytical Chemistry, a team of scientists led by Steven A. Soper is working on a new blood test that could swiftly diagnose not only whether...Read more

2013 03 Oct

A Yale-led study has identified a gene expression profile that can predict outcomes and lead to better treatment for one of the most lethal lung diseases, idiopathic pulmonary fibrosis (IPF). The study appears in Science Translational Medicine. IPF causes progressive scarring of the lungs, leading to cough, shortness of breath, and potentially death....Read more

2013 25 Sep

Mayo Clinic researchers have shown that a specific protein pair may be a successful prognostic biomarker for identifying smoking-related lung cancers. The protein — ASCL1 — is associated with increased expression of the RET oncogene, a particular cancer-causing gene called RET. The findings appear in the online issue of the journal Oncogene. "This...Read more

2013 06 Sep

Hospital laboratories outside the U.S. can benefit from a continued availability of the B·R·A·H·M·S PCT™ assay on ADVIA Centaur® systems, allowing them to diagnose sepsis early and safely. Thermo Fisher and Siemens Healthcare Diagnostics renew their non-exclusive, long-term, royalty-bearing agreement for the use of...Read more

2013 01 Aug

Abbott announced on July 30, 2013, promising results from a study evaluating its High Sensitive Troponin-I (hsTnI) assay presented at this year’s American Association for Clinical Chemistry (AACC) annual meeting in Houston, Texas. The study, conducted by researchers at Brigham and Women’s Hospital, demonstrated that Abbott’s hsTnI test (currently...Read more

2013 18 Jun

A team from the University of Toronto – including researchers from Electrical and Computer Engineering and the Institute of Biomaterials & Biomedical Engineering – has created an electronic chip that can analyze blood and other clinical samples for infectious bacteria with record-breaking speed. Life-threatening bacterial infections...Read more

2013 06 Jun

Astute Medical, Inc. will host an educational symposium bringing together an international panel of medical experts to discuss how newly validated biomarkers of acute kidney injury (AKI) risk can improve care of critically ill patients in the intensive care setting. The symposium, AKI Biomarkers of Risk Assessment: A New Age , will take place...Read more

2013 06 Jun

Two biomarkers widely being investigated as predictors of heart and vascular disease appear to indicate risk for "silent" strokes and other causes of mild brain damage that present no symptoms, report researchers from The Methodist Hospital and several other institutions in an upcoming issue of Stroke (now online). The researchers found high...Read more

2013 04 Jun

Critical Diagnostics’ novel cardiac biomarker, ST2, could offer a way for doctors to monitor transplant patients versus expensive and risky biopsies Critical Diagnostics announced on May 22, 2013, the recently-published results of a Utah Transplantation Affiliated Hospitals Cardiac Transplant Program study involving the use of a novel biomarker,...Read more

2013 14 Mar

Thermo Scientific will be exhibiting at the 33 rd ISICEM in Brussels and will be presenting its procalcitonin (PCT) biomarker. Early identification of sepsis is crucial to improving patient outcomes. Yet sepsis can be difficult to differentiate from nonbacterial infections. Procalcitonin (PCT) is a biomarker that exhibits a rapid, clinically...Read more

2013 14 Mar

Satellite Symposium: Point of care cardio-renal biomarkers have changed my practice: A debate Location: 400 Hall Chairperson: Claudio Ronco (Vicenza, Italy) Time: March 20, 2013 at 12:30 Programme (12:30-13:30) Introduction FOR: Current clinical practice of cardio-renal biomarkers in the ED Salvatore Di Somma (Rome, Italy) FOR:...Read more

2013 14 Mar

BioPorto Diagnostics will be exhibiting at the 33rd ISICEM in Brussels and will be presenting the The NGAL Test™ . The NGAL Test™ CE IVD is a new rapid NGAL assay for clinical chemistry platforms.* Using only a few drops of plasmaor urine The NGAL Test™ gives you results in just 10 minutes and thus addresses the widespread demand for urgent...Read more

2013 14 Mar

Satellite Symposium: New Biomarkers for Early Risk Assessment of AKI: Solving the Challenge Location: Horta Room Chairperson: John Kellum (Pittsburgh, USA) Time: March 20, 2013 at 12:30 Programme (12:30-13:30)  Welcome and Introduction - John Kellum (Pittsburgh, USA)  Cell Cycle Arrest Biomarkers for AKI - Lakhmir Chawla (Washington,...Read more

2013 14 Mar

A guidance cue that helps kidneys form may also be a red flag that they are in danger, researchers report. Acute kidney injury, a common and serious complication of hospitalization, is on the increase worldwide, affecting an estimated 6 percent of all hospitalized patients and 30-40 percent of adults and children having cardiopulmonary bypass surgery....Read more

2013 06 Mar

Alere Inc. is pleased to announce the results of a study published this week in Critical Care, demonstrating that plasma neutrophil gelatinase-associated lipocalin (pNGAL), a biomarker that aids in the early detection of acute kidney injury (AKI), improved the diagnosis of AKI when added to clinical judgment. Patients presenting to the emergency department...Read more