Search Tag: ARDS
2019 25 Jul
Diagnosis of the Influenza virus remains a challenge in the ICU. It is vital that knowledge of its pathophysiology and epidemiology is known so clinicians can make informed decisions regarding their patients’ health. The Influenza virus is found most commonly to replicate in the respiratory tract in humans. This is mainly due to the haemagglutinin...Read more
2019 30 May
Interview with Rolf Rossaint, Prof. of Anaesthesiology, RWTH University Aachen, Germany. Rolf Rossaint is a Professor and Chairman of the Department of Anaesthesiology of the University Hospital at the RWTH University Aachen, Germany. Prof. Rossaint has published several high-quality studies dealing with the treatment of severe acute respiratory...Read more
2019 30 May
According to a National Institutes of Health sponsored clinical trial that was conducted at several North American hospitals and was led by clinician-scientists at the University of Pittsburgh and University of Colorado schools of medicine, reversibly paralysing and sedating hospitalised patients with severe breathing problems does not prove improve...Read more
2019 22 Mar
At the 39th International Symposium on Intensive Care and Emergency Medicine , Professor V. Marco Ranieri , University of Bologna, discussed the SUPERNOVA trial and presented an overview on extracorporeal carbon dioxide removal (ECCO 2 R) as a supportive measure in superprotective lung ventilation. Mechanical ventilation can cause a form...Read more
2019 14 Mar
Susan East, a patient speaker at the ATS 2017 International Conference in Washington D.C. and a three times ARDS survivor shares her experience about her stay in the ICU. I am Susan East, a three times ARDS survivor. July 3, 2008, I had ARDS! I went to my primary physician on June 30, 2008 with symptoms of a sinus infection. He diagnosed...Read more
2019 12 Mar
At least one fifth of all patients admitted to the ICU are obese, and these patients are at risk of developing lung de-recruitment and then atelectasis. Moreover, the incidence of acute respiratory distress syndrome (ARDS) is increased in obese patients. A major challenge of the critical care management of obese patients is successful...Read more
2019 12 Mar
Adjusting positive end-expiratory pressure (PEEP) to offset pleural pressure might attenuate lung injury and improve patient outcomes in acute respiratory distress syndrome (ARDS). Researchers conducted a multicentre randomised clinical trial to determine whether PEEP titration guided by oesophageal pressure (PES), an estimate of pleural pressure,...Read more
2019 05 Mar
There have been multiple advances in the management of acute respiratory distress syndrome (ARDS), but the temporal trends in ARDS-related mortality are not well known. Conservative fluid management strategy for ARDS, in particular, has been extensively studied and is increasingly being used in clinical practice. However, it is largely unknown whether...Read more
2019 23 Jan
Previous studies have suggested that the effects of spontaneous breathing during mechanical ventilation in acute respiratory distress syndrome (ARDS) may depend on ARDS etiology and severity, with possible beneficial effects in mild to moderate ARDS and harmful effects in severe ARDS. However, a new analysis did not find an association between ARDS...Read more
2018 11 Dec
The consensus definitions of acute respiratory distress syndrome (ARDS) mainly rely on feasible clinical criteria, which help to group patients together for inclusion in clinical trials and for clinical management. This generates clinical and biological differences in observable patient characteristics. These differences could be used to group ARDS...Read more
2018 11 Dec
Acute respiratory distress syndrome (ARDS) results in substantial mortality but remains underdiagnosed in clinical practice. For this reason, automated “sniffer” systems that analyse electronic records have been developed to assist clinicians with ARDS diagnosis. However, a new systematic review found that these sniffer tools had moderate to high predictive...Read more
2018 04 Dec
If you landed here from ICU Highlights e-newsletter you may be looking for New protocol for respiratory infectious disease diagnosis in ICU. Hospital mortality in acute respiratory distress syndrome (ARDS) is approximately 40 percent, but mortality and trajectory in “mild” ARDS – classified only since 2012 – are unknown. A new study finds that...Read more
2018 18 Jul
A new systematic review and meta-analysis shows that chronic high alcohol consumption significantly increases the risk of acute respiratory distress syndrome (ARDS). This finding suggests that patients admitted to hospital should be screened for chronic alcohol use, according to researchers at the University of Nottingham's UK Centre for Tobacco...Read more
2018 27 Jun
A new analysis shows that biomarkers of intravascular monocyte activation in at-risk patients were associated with the development of acute respiratory distress syndrome (ARDS). Further, the potential clinical benefit of early aspirin for prevention of ARDS remains uncertain, according to the findings reported in the American Journal of Respiratory...Read more
2018 01 Jun
A comparison of hospital admissions of patients over 65 and air pollution in the USA has found an association between exposure to pollutants and admission for acute respiratory distress syndrome (ARDS). The study was presented at the annual meeting of the American Thoracic Society. The researchers analysed data by zip code from nearly 30 million...Read more
2018 15 May
A new analysis of data from patients enrolled in high-quality ARDSnet trials showed no difference between patients with moderate-severe and mild-moderate ARDS in terms of mortality, even though there were differences in rapid resolution of ARDS, ventilator-free days and ICU-free days. The research is published online in Annals of the American Thoracic...Read more
2018 16 Mar
CO 2 exerts potent effects on lung biology that could be clinically relevant in critically ill patients, in particular those with acute respiratory distress syndrome (ARDS). The impact of hypercapnia on outcome in these patients is yet to be determined. The physiological effects of hypercapnia are increasingly well understood, but the literature...Read more
2018 21 Feb
Acute respiratory distress syndrome (ARDS) often requires prolonged and complicated hospital courses putting patients at risk for intensive care unit (ICU) delirium. Antipsychotics are prescribed to decrease the severity and duration of ICU delirium; however, these drugs are associated with many adverse effects including respiratory failure. "Given...Read more
2018 15 Jan
Traumatic brain injury (TBI) patients frequently suffer from lung complications and acute respiratory distress syndrome (ARDS), which is associated with poor clinical outcomes. However, there are inadequate data addressing the safety or efficacy of ventilator strategies used in ARDS in adult patients with TBI, says an article published in Journal of...Read more
2018 08 Jan
The acute respiratory distress (ARDS) lung is usually characterised by a high degree of inhomogeneity. Indeed, the same lung may show a wide spectrum of aeration alterations, ranging from completely gasless regions, up to hyperinflated areas, explain Luciano Gattinoni, Tommaso Tonetti and Michael Quintel in an article published in the journal Critical...Read more
2018 08 Jan
Failure to reliably diagnose ARDS, or acute respiratory distress syndrome, could lead to underrecognition and undertreatment in clinical practice. New research shows the reliability of the Berlin ARDS definition is "moderate," driven primarily by differences in chest imaging interpretation. The study is in press in the journal CHEST. The 2012 revision...Read more
2017 14 Nov
The acute respiratory distress syndrome (ARDS) was first reported in 1967. Upon the occasion of its 50th birthday, ARDS is due for a midlife crisis, says Dr. Robert P. Dickson, of the Division of Pulmonary and Critical Care Medicine, University of Michigan Health System. "In our era of molecular medicine, ARDS seems a bit stuck in the past," he writes...Read more
2017 01 Nov
Previous research suggests that lung recruitment manoeuvres (LRMs) may prevent ventilator-induced lung injury and improve survival in patients with acute respiratory distress syndrome (ARDS). Now a new systematic review indicates that LRMs in combination with a higher positive end-expiratory pressure (PEEP) ventilation strategy reduce mortality. However,...Read more
2017 05 Oct
Despite proven benefits of proning patients with ARDS ( Guérin et al. 2013 ), patients with ARDS are seldom put in prone position. A one-day prevalence study of prone positioning in ARDS patients, organised by the European Society of Intensive Care Medicine (ESICM) Acute Respiratory Failure Section, found low rates of proning, similar to those...Read more
2017 19 Sep
Acute respiratory distress syndrome (ARDS) is a common condition in intensive care unit patients and remains a major concern, with mortality rates of around 30-45% and considerable long-term morbidity. In an opinion document published in the journal Critical Care, international experts review the available clinical evidence related to ventilator support...Read more
2017 07 Jun
A number of supportive therapies have reduced mortality in acute respiratory distress syndrome (ARDS), including lung-protective mechanical ventilation, neuromuscular blockade, and prone positioning. Fluid-conservative therapy has also increased ventilator-free days in patients with ARDS. However, the lack of success of pharmacological therapies...Read more
2017 28 May
How Acute Respiratory Distress Syndrome Changed My Life in a Split Second Life changed forever when Eileen Rubin was hospitalised with ARDS. After a slow recovery it was time to give something back, and Eileen went on to co-found the ARDS Foundation. “I can’t breathe. I think I’m dying.” Those were the words I gasped to my mother less than...Read more
2017 22 May
Analysis of data from the large French CUB-REA database indicates that mortality from acute respiratory distress syndrome (ARDS) was lower in high-volume ICUs than low and moderate volume ICUs. Notably, between 2000 and 2014, among 35 ICUs in the CUB-REA registry, ICU mortality decreased despite an increase in ARDS severity. The findings were presented...Read more