Search Tag: ARDS

ICU Management

Management-of-obese-patients-with-ards

2019 12 Mar

At least one fifth of all patients admitted to the ICU are obese, and these patients are at risk of developing lung de-recruitment and then atelectasis. Moreover, the incidence of acute respiratory distress syndrome (ARDS) is increased in obese patients.   A major challenge of the critical care management of obese patients is successful...Read more

ICU Management

New-findings-don-t-support-pes-guided-peep-titration-in-ards

2019 12 Mar

Adjusting positive end-expiratory pressure (PEEP) to offset pleural pressure might attenuate lung injury and improve patient outcomes in acute respiratory distress syndrome (ARDS). Researchers conducted a multicentre randomised clinical trial to determine whether PEEP titration guided by oesophageal pressure (PES), an estimate of pleural pressure,...Read more

ICU Management

Declining-rate-of-ards-related-mortality

2019 05 Mar

There have been multiple advances in the management of acute respiratory distress syndrome (ARDS), but the temporal trends in ARDS-related mortality are not well known. Conservative fluid management strategy for ARDS, in particular, has been extensively studied and is increasingly being used in clinical practice. However, it is largely unknown whether...Read more

ICU Management

Effects-of-spontaneous-breathing-during-ventilation-in-ards

2019 23 Jan

Previous studies have suggested that the effects of spontaneous breathing during mechanical ventilation in acute respiratory distress syndrome (ARDS) may depend on ARDS etiology and severity, with possible beneficial effects in mild to moderate ARDS and harmful effects in severe ARDS. However, a new analysis did not find an association between ARDS...Read more

ICU Management

Phenotyping-need-to-identify-subgroups-of-ards-patients

2018 11 Dec

The consensus definitions of acute respiratory distress syndrome (ARDS) mainly rely on feasible clinical criteria, which help to group patients together for inclusion in clinical trials and for clinical management. This generates clinical and biological differences in observable patient characteristics. These differences could be used to group ARDS...Read more

ICU Management

Are-sniffer-systems-effective-in-detecting-ards

2018 11 Dec

Acute respiratory distress syndrome (ARDS) results in substantial mortality but remains underdiagnosed in clinical practice. For this reason, automated “sniffer” systems that analyse electronic records have been developed to assist clinicians with ARDS diagnosis. However, a new systematic review found that these sniffer tools had moderate to high predictive...Read more

ICU Management

Closer-monitoring-needed-for-patients-with-mild-ards

2018 04 Dec

If you landed here from ICU Highlights e-newsletter you may be looking for New protocol for respiratory infectious disease diagnosis in ICU. Hospital mortality in acute respiratory distress syndrome (ARDS) is approximately 40 percent, but mortality and trajectory in “mild” ARDS – classified only since 2012 – are unknown. A new study finds that...Read more

ICU Management

Chronic-high-alcohol-consumption-increases-ards-risk

2018 18 Jul

A new systematic review and meta-analysis shows that chronic high alcohol consumption significantly increases the risk of acute respiratory distress syndrome (ARDS). This finding suggests that patients admitted to hospital should be screened for chronic alcohol use, according to researchers at the University of Nottingham's UK Centre for Tobacco...Read more

ICU Management

Early-intravascular-events-may-contribute-to-ards-development

2018 27 Jun

A new analysis shows that biomarkers of intravascular monocyte activation in at-risk patients were associated with the development of acute respiratory distress syndrome (ARDS). Further, the potential clinical benefit of early aspirin for prevention of ARDS remains uncertain, according to the findings reported in the American Journal of Respiratory...Read more

ICU Management

Study-air-pollution-associated-with-ards-hospitalisation-in-over-65s

2018 01 Jun

A comparison of hospital admissions of patients over 65 and air pollution in the USA has found an association between exposure to pollutants and admission for acute respiratory distress syndrome (ARDS). The study was presented at the annual meeting of the American Thoracic Society.   The researchers analysed data by zip code from nearly 30 million...Read more

ICU Management

Ards-reclassification-the-debate-continues

2018 15 May

A new analysis of data from patients enrolled in high-quality ARDSnet trials showed no difference between patients with moderate-severe and mild-moderate ARDS in terms of mortality, even though there were differences in rapid resolution of ARDS, ventilator-free days and ICU-free days. The research is published online in Annals of the American Thoracic...Read more

ICU Management

Volume-18-issue-1-2018-1

2018 16 Mar

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ICU Management

Co2-in-the-critically-ill

2018 16 Mar

CO 2 exerts potent effects on lung biology that could be clinically relevant in critically ill patients, in particular those with acute respiratory distress syndrome (ARDS). The impact of hypercapnia on outcome in these patients is yet to be determined. The physiological effects of hypercapnia are increasingly well understood, but the literature...Read more

ICU Management

Ards-delirium-and-antipsychotic-use-reviewed

2018 21 Feb

Acute respiratory distress syndrome (ARDS) often requires prolonged and complicated hospital courses putting patients at risk for intensive care unit (ICU) delirium. Antipsychotics are prescribed to decrease the severity and duration of ICU delirium; however, these drugs are associated with many adverse effects including respiratory failure. "Given...Read more

ICU Management

Managing-ards-in-traumatic-brain-injury

2018 15 Jan

Traumatic brain injury (TBI) patients frequently suffer from lung complications and acute respiratory distress syndrome (ARDS), which is associated with poor clinical outcomes. However, there are inadequate data addressing the safety or efficacy of ventilator strategies used in ARDS in adult patients with TBI, says an article published in Journal of...Read more

ICU Management

Making-mechanical-ventilation-safe-for-ards

2018 08 Jan

The acute respiratory distress (ARDS) lung is usually characterised by a high degree of inhomogeneity. Indeed, the same lung may show a wide spectrum of aeration alterations, ranging from completely gasless regions, up to hyperinflated areas, explain Luciano Gattinoni, Tommaso Tonetti and Michael Quintel in an article published in the journal Critical...Read more

ICU Management

Can-we-improve-the-reliability-of-ards-diagnosis

2018 08 Jan

Failure to reliably diagnose ARDS, or acute respiratory distress syndrome, could lead to underrecognition and undertreatment in clinical practice. New research shows the reliability of the Berlin ARDS definition is "moderate," driven primarily by differences in chest imaging interpretation. The study is in press in the journal CHEST. The 2012 revision...Read more

ICU Management

After-50-years-ards-stuck-in-the-past

2017 14 Nov

The acute respiratory distress syndrome (ARDS) was first reported in 1967. Upon the occasion of its 50th birthday, ARDS is due for a midlife crisis, says Dr. Robert P. Dickson, of the Division of Pulmonary and Critical Care Medicine, University of Michigan Health System. "In our era of molecular medicine, ARDS seems a bit stuck in the past," he writes...Read more

ICU Management

Are-lung-recruitment-manoeuvres-beneficial-to-ards-patients

2017 01 Nov

Previous research suggests that lung recruitment manoeuvres (LRMs) may prevent ventilator-induced lung injury and improve survival in patients with acute respiratory distress syndrome (ARDS). Now a new systematic review indicates that LRMs in combination with a higher positive end-expiratory pressure (PEEP) ventilation strategy reduce mortality. However,...Read more

ICU Management

Lives-2017-lack-of-severe-hypoxaemia-most-common-reason-not-to-prone

2017 05 Oct

Despite proven benefits of proning patients with ARDS ( Guérin et al. 2013 ), patients with ARDS are seldom put in prone position. A one-day prevalence study of prone positioning in ARDS patients, organised by the European Society of Intensive Care Medicine (ESICM) Acute Respiratory Failure Section, found low rates of proning, similar to those...Read more

ICU Management

Respiratory-support-in-ards-an-expert-opinion

2017 19 Sep

Acute respiratory distress syndrome (ARDS) is a common condition in intensive care unit patients and remains a major concern, with mortality rates of around 30-45% and considerable long-term morbidity. In an opinion document published in the journal Critical Care, international experts review the available clinical evidence related to ventilator support...Read more

ICU Management

Clinical-trials-in-ards-challenges-and-opportunities

2017 07 Jun

A number of supportive therapies have reduced mortality in acute respiratory distress syndrome (ARDS), including lung-protective mechanical ventilation, neuromuscular blockade, and prone positioning. Fluid-conservative therapy has also increased ventilator-free days in patients with ARDS. However, the lack of success of pharmacological therapies...Read more

ICU Management

Volume-17-issue-2-2017-1

2017 28 May

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ICU Management

From-independent-attorney-to-critically-ill-patient

2017 28 May

How Acute Respiratory Distress Syndrome Changed My Life in a Split Second Life changed forever when Eileen Rubin was hospitalised with ARDS. After a slow recovery it was time to give something back, and Eileen went on to co-found the ARDS Foundation.   “I can’t breathe. I think I’m dying.” Those were the words I gasped to my mother less than...Read more

ICU Management

Ards-treat-high-volume-lower-mortality

2017 22 May

Analysis of data from the large French CUB-REA database indicates that mortality from acute respiratory distress syndrome (ARDS) was lower in high-volume ICUs than low and moderate volume ICUs. Notably, between 2000 and 2014, among 35 ICUs in the CUB-REA registry, ICU mortality decreased despite an increase in ARDS severity. The findings were presented...Read more

ICU Management

Economic-cost-to-surviving-ards-new-study

2017 28 Apr

Research published today in the American Journal of Respiratory and Critical Care Medicine sheds light on the economic toll on survivors of acute respiratory distress syndrome. Nearly fifty percent of survivors who worked before they were ill were not working after a year, and lost nearly two-thirds of their annual income. The researchers estimated...Read more

ICU Management

A-second-opinion

2017 18 Apr

What would you single out as a career highlight? Combining my loves of medicine and art to create a colouring book about the brain, entitled 'A Journey Through the Brain'. This was a collaboration with the very creative and intelligent Prof David Cotter and Prof Mary Cannon at the Department of Psychiatry in RCSI. If you had not chosen this career...Read more

ICU Management

Volume-17-issue-1-2017-1

2017 16 Mar

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ICU Management

Towards-safer-ventilation-in-critically-ill-patients-without-ards

2017 16 Mar

Invasive ventilatory support, one of the most frequently applied strategies in intensive care unit (ICU) patients, is increasingly recognised as a potentially dangerous intervention. Recognition of so–called ventilator– induced lung injury and the broad acceptance of lung–protective ventilation strategies in ICUs worldwide led to noticeable changes...Read more

ICU Management

Acute-respiratory-distress-syndrome-ards-and-quality-of-life

2016 01 Aug

Critical care researchers from Intermountain Medical Center in Salt Lake City conducted a study with 616 patients treated for Acute Respiratory Distress Syndrome (ARDS), a progressive condition that often occurs in patients who are critically ill or who have significant trauma injuries . The aim of the study was to determine factors that played a significant...Read more