Search Tag: ARDS

ICU Management

Insights-from-the-provent-covid-study

2021 23 Aug

Mortality in patients with COVID-19 is much higher in patients who need invasive ventilation for acute respiratory distress syndrome (ARDS). COVID-19 patients with ARDS are a heterogeneous group with diverse evolutions that could be due to different phenotypes and response to care, including invasive ventilation strategies.   The Practice of VENTilation...Read more

ICU Management

Prone-positioning-during-ecmo-for-ards

2021 17 Aug

There is sufficient evidence to show that prone positioning improves oxygenation and respiratory mechanics and is also associated with lower mortality in patients with moderate to severe ARDS. However, some patients can develop refractory hypoxaemia and hypercapnia that could require the use of venovenous extracorporeal membrane oxygenation (VV-ECMO)...Read more

ICU Management

Precision-therapies-for-heterogeneous-ards-patients

2021 20 Jul

ARDS is a heterogeneous syndrome rather than a distinct disease. It is this heterogeneity that often makes it difficult to study treatments for patients with ARDS. Literature on ARDS is rife with clinical trials that do not show any mortality benefit.   Recent evidence suggests different sub-phenotypes within the heterogeneous patient population....Read more

ICU Management

Association-of-higher-vs-lower-peep-on-mortality

2021 19 Jul

Mechanical ventilation is a life-saving strategy for critically ill patients. However, it can promote and/or exacerbate lung injury through several mechanisms, including alveolar overdistension and repetitive opening and closing of the alveoli and small airways. Positive end-expiratory pressure (PEEP) has been employed to prevent end-expiratory alveolar...Read more

ICU Management

Selection-criteria-for-lung-transplantation-in-covid-19-patients

2021 06 Apr

In May 2020, a team led by thoracic surgeon Konrad Hoetzenecker of the Department of Surgery of MedUni Vienna and Vienna General Hospital performed a lung transplant on a 44-year-old patient who had been seriously ill with COVID-19. She thus became the first patient in Europe to receive a lung transplant for this indication. The Vienna lung transplantation...Read more

ICU Management

Corticosteroid-treatment-in-ards

2021 30 Mar

Acute respiratory distress syndrome (ARDS) is a life-threatening condition that is characterised by bilateral pulmonary infiltrates on chest imaging and refractory hypoxaemia. ARDS is common in critically ill patients in ICUs and is associated with significant mortality. Findings from a recent study show that approximately 10% of ICU patients suffered...Read more

ICU Management

Volume-21-issue-1-2021-1

2021 24 Feb

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ICU Management

How-should-we-manage-sedation-in-critically-ill-covid-19-patients

2021 22 Feb

Clinical Practice Guidelines The Choosing Wisely top five guidelines published a few years ago by the Chest Association of Physicians, the American Thoracic Society, the Society of Critical Care Medicine, and the American Association of Critical Care Nurses state that mechanically ventilated patients should not be deeply sedated without a specific...Read more

ICU Management

Important-questions-answered

2021 22 Feb

During the question/answer session, Prof Vito Marco Ranieri discussed some important questions with Prof Salvatore Maurizio Maggiore and Prof Boris Jung regarding sedation regimen, respiratory muscle paralysis, sedation in COVID-19 patients specifically and how it is different from other regular ICU patients. Ranieri: What is your opinion...Read more

ICU Management

Prone-position-in-awake-non-intubated-patients-with-ards-from-physiology-to-the-bedside

2021 22 Feb

Prone position (PP) in awake, non-intubated patients with respiratory failure is a physiology-based ventilatory strategy that improves oxygenation and may decrease the need for intubation and invasive mechanical ventilation (IMV). Introduction During the pandemic caused by the SARS-CoV-2 virus, which produces coronavirus disease...Read more

ICU Management

Optimising-patient-care-during-covid-19-the-four-ps

2021 31 Jan

The COVID-19 pandemic has had a significant impact on ICUs around the world. Most healthcare systems were prepared to handle natural disasters or accidents, but as we have all witnessed, they were unprepared to handle the massive influx of patients during the COVID-19 crisis. Last year was quite a challenge for healthcare providers around the world,...Read more

ICU Management

Do-we-need-to-diagnose-ards

2020 19 Oct

Acute respiratory distress syndrome (ARDS) is the clinical expression of acute, non-haemodynamic lung oedema. It is typically diagnosed by hypoxaemia, and bilateral lung infiltrates in the absence of increased capillary hydrostatic pressure. ARDS represents nearly a quarter of the ICU patients who require mechanical ventilation. There is significant...Read more

ICU Management

Lung-histopathology-covid-19-compared-to-sars-h1n1

2020 09 Oct

The coronavirus disease has spread throughout the world and has resulted in many challenges for healthcare systems. It is a new disease with a significant burden of respiratory failure. This has led to questions about the pathogenesis and pulmonary pathology of COVID-19.   Patients with severe COVID-19 have respiratory failure with hypoxaemia,...Read more

ICU Management

Covid-19-induced-respiratory-failure-and-ards

2020 02 Sep

Approximately 5% of patients infected by COVID-19 require ICU admission due to acute respiratory distress syndrome (ARDS). Invasive mechanical ventilation is required in a large majority of these patients. Proper ventilatory management during ARDS reduces the risk of ventilator-induced lung injury and can also play a role in improving patient survival....Read more

ICU Management

Getinge-receives-510-k-clearance-from-us-fda-for-the-servo-air-r-mechanical-ventilator

2020 07 Jul

Getinge has received 510(k) clearance from the US Food & Drug Administration (FDA) for the company’s Servo-air® mechanical ventilator, which is part of the Servo family that supports intensive care ventilation ever since the first model was introduced in 1971. "We are happy to be able to help clinicians in their endeavor to save lives by adding...Read more

ICU Management

What-is-the-relevance-of-cytokine-storm-to-covid-19

2020 05 Jul

COVID-19, in its most severe form, leads to life-threatening pneumonia and acute respiratory distress syndrome (ARDS). In patients with this severity of the coronavirus, mortality rate can approach 40 to 50%.    The mechanism of COVID-19 induced lung injury is still vague, but the term cytokine storm is being used quite frequently in scientific publications...Read more

ICU Management

Pulmonary-pathobiology-of-covid-19

2020 27 May

The primary cause of death with COVID-19 is progressive respiratory failure. However, despite the widespread infection rates associated with COVID, very little is known about the pathophysiology of the disease. What clinicians do know is that the pathological features resemble acute respiratory distress syndrome (ARDS) and progressive hypoxia. But...Read more

ICU Management

Managing-covid-19-respiratory-distress

2020 30 Apr

Acute respiratory stress syndrome is one of the primary ways COVID-19 infection manifests in the patient. COVID-19 injures the vascular endothelium, which can lead to multiorgan failure even in young patients without any comorbidities. A wide variation in mortality rates indicates that the key to improving outcomes of ventilatory support could be in...Read more

ICU Management

Amomed-pharma-offers-drugs-for-severe-covid-19-cases

2020 23 Apr

AMOMED Pharma develops medicinal products for patients suffering from septic shock at the intensive care units. Septic shock is a life-threatening complication in COVID-19 patients.   Most COVID-19 admissions to the intensive care unit are due to severe lung disorders requiring invasive mechanical ventilation; many with acute respiratory distress...Read more

ICU Management

Is-covid-19-pneumonia-ards-or-not

2020 18 Apr

COVID-19 pneumonia meets the ARDS Berlin definition. However, it is a specific disease with peculiar phenotypes. The primary characteristic is the dissociation between the severity of the hypoxaemia and the maintenance of respiratory mechanics. Patients with respiratory compliance that is lower or higher than the median value experience severe hypoxaemia. ...Read more

ICU Management

Coronavirusoutbreak-caring-for-the-critically-ill-trends-treatment-and-mortality

2020 16 Mar

COVID-19 is associated with severe disease requiring intensive care in approximately 5% of proven infections. As with similar outbreaks in the past, including SARS, MERS, A(H7N9), and H1N1, critical care continues to be an integral component of the global response to Coronavirus. You might also like :  Coronavirus and the Potential Role of ECMO...Read more

ICU Management

Top-icu-stories-of-2019

2019 28 Dec

As we move into 2020, here's a quick recap of our most clicked stories in ICU in 2019:  Using Biomarkers for Mortality Prediction in Patients With Sepsis A new study evaluated the prognostic value of six biomarkers at onset of sepsis in adult patients with sepsis or septic shock. Risk Factors for Frailty and Death in the ICU...Read more

ICU Management

Risk-factors-for-ards-in-mechanically-ventilated-adults

2019 16 Dec

Acute respiratory distress syndrome (ARDS) is an inflammatory process that could lead to diffuse oedema and hypoxaemic respiratory failure. It is also characterised by increased pulmonary vascular permeability, increased lung weight, and loss of aerated lung. In low and middle-income countries, ARDS mortality ranges from 26 to 58%.  A large majority...Read more

ICU Management

Cognitive-impairment-after-ards

2019 22 Nov

Acute respiratory distress syndrome (ARDS) is a serious disorder that causes severe hypoxia requiring mechanical ventilation. It affects approximately 200,000 patients in the US each year, accounting for 10% of ICU admissions and a mortality risk of 25-40%. In many cases, patients also develop dysfunction of other organs that leads to high morbidity...Read more

ICU Management

Lives2019-vitamin-c-for-sepsis

2019 04 Oct

Dr. Alpha A. Fowler of Virginia Commonwealth University presented findings from the CITRIS-ALI trial that studied the role of vitamin C in patients with septic ARDS. The findings were presented @ESICM in Berlin and have just been published in JAMA.  The CITRIS-ALI randomised trial addressed the use of high dose intravenous vitamin C to study...Read more

ICU Management

Nutrition-2

2019 26 Sep

The critically ill patient is often unable to feed by mouth. This condition, in some patients, can range from days to months. It is imperative that these patients receive macronutrients either through enteral or parenteral nutrition. If they don't, there is a risk of an energy deficit that could lead to loss of lean body mass and subsequently, other...Read more

ICU Management

Noninvasive-ventilation-in-early-stage-mild-ards

2019 06 Sep

A recent study assessed the ability of early noninvasive ventilation (NIV) intervention to decrease the need for invasive ventilation in patients with mild forms of acute respiratory distress syndrome (ARDS). This method has already proved successful for acute respiratory failure patients but has not been tested in ARDS.   Use of NIV in ARDS patients...Read more

ICU Management

Lung-recruitment-in-patients-with-severe-ards

2019 30 Aug

Acute Respiratory Distress Syndrome (ARDS) affects up to 10% of patients in the ICU. Typical symptoms of ARDS include an increase in lung weight and a reduction of aerated lung tissue. For the treatment of ARDS alveolar recruitment is key, however, this has not yet been shown to benefit severe ARDS cases. It has been suggested that lung recruitment...Read more

ICU Management

Personalised-mechanical-ventilation-the-live-study

2019 18 Aug

The effectiveness of personalised mechanical ventilation in patients with acute respiratory distress syndrome (ARDS) is still unclear. A new study was conducted in France to test whether a mechanical ventilation strategy personalised to an individual patient's lung morphology could improve survival compared with the standard of care.  For the...Read more

ICU Management

Understanding-the-influenza-virus

2019 25 Jul

Diagnosis of the Influenza virus remains a challenge in the ICU. It is vital that knowledge of its pathophysiology and epidemiology is known so clinicians can make informed decisions regarding their patients’ health.   The Influenza virus is found most commonly to replicate in the respiratory tract in humans. This is mainly due to the haemagglutinin...Read more