Search Tag: insulin
Dysglycaemia in the critically ill
2018 16 Mar
As has been pointed out, the benefits of tight glycaemic control in the ICU have by no means been clearly established or accepted. In 2010 a meta-analysis of seven prospective randomised studies concluded that intensive insulin therapy in mixed ICU patients was not supported by evidence. 19 Today we understand that hyperglycaemia, hypoglycaemia,... Read more
Insulin Resistance Increases Risk for Alzheimer's Disease
2015 28 Jul
An imaging study finds a strong association between insulin resistance and lower brain glucose metabolism in a group of late middle-age adults at risk for Alzheimer's disease (AD). The findings are published online in JAMA Neurology. Insulin resistance, broadly defined as reduced tissue responsiveness to the action of insulin, is common in people who... Read more
Researcher Discovers a Way to Prevent Type 1 Diabetes
2015 27 Jan
According to new research published in Endocrinology , Thomas Burris, Ph.D., chair of pharmacological and physiological science at Saint Louis University and his team have found a way to prevent type 1 diabetes in an animal model. The team comprised of Laura A. Solt, Subhashis Banerjee, Sean Campbell and Theodore M. Kamenecka. Current available... Read more
Sanofi And MannKind To Launch Inhalable Insulin
2014 14 Nov
MannKind and Sanofi are set to launch their inhalable insulin product. Approved earlier this year by the FDA, Afrezza is a fast-acting insulin to be taken at mealtimes. The drug is effective for both Type 1 and Type 2 diabetes. Seven years ago, Pfizer launched Exubera, another inhalable insulin. When Exubera was introduced, it was believed to... Read more
Novel Capsule Could Replace Injections
2014 03 Oct
Researchers at MIT and Massachusetts General Hospital (MGH) have devised a novel drug capsule that is coated with tiny needles and that can be used to inject drugs directly into the lining of the stomach once the capsule is swallowed. The drug capsule has been designed by Carl Schoellhammer, Giovanni Traverso and their colleagues. They have developed... Read more
Implantable Device Controls Insulin Production
2014 12 Aug
A team of bioengineers from ETH Zurich's Department of Biosystems Science and Engineering (D-BSSE) in Basel, Switzerland, have developed an implantable molecular device that is composed of two modules: a sensor that can measure blood pH constantly, and a gene feedback mechanism that produces the necessary amount of insulin. Both modules have been constructed... Read more