Hypomagnesemia in Critically Ill patients on Kidney Replacement Therapy

Hypomagnesemia is a common electrolyte disorder in critically ill patients and is associated with increased morbidity and mortality risk. Many clinical conditions may contribute to hypomagnesemia through different pathogenetic mechanisms. In patients with acute kidney injury (AKI) the need for continuous or prolonged intermittent kidney replacement therapy (CKRT and PIKRT, respectively) may further add to other causes of hypomagnesemia, especially when regional citrate anticoagulation (RCA) is used. Dr. DiMario will explore strategies aimed at how precisely tailoring both dialysis prescriptions and the composition of KRT fluids, as well as early magnesium supplementation and close monitoring, could represent a cornerstone in reducing KRT-related hypomagnesemia.

Dr. Ferrari will discuss the limitations of serum magnesium as a standard lab test and the advantages of ionized magnesium (iMg) testing for more effective management of dysmagnesemia in critically ill patients.

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